Mohammed Abdul Jawad

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Bacterial Genomes I: From DNA to Protein Function Using Bioinformatics


Bacterial Genomes I: From DNA to Protein Function Using Bioinformatics


FREE ONLINE COURSE (with a PDF Certificate of Achievement to prove your success when you’re eligible)

  • Duration: 2 weeks


This introductory course will show you the power of bioinformatics to explore bacterial DNA and bacterial and pathogen biology.


Join us in our quest to discover what makes microbes dangerous. Use bioinformatics to probe genomes, to explore and represent DNA and protein sequences. Then, use databases to find protein sequences’ conserved domains and investigate their functions.



SYLLABUS

Week 1

Introduction to DNA and protein sequences


Welcome to the Course: Welcome to 'From DNA to Protein Function Using Bioinformatics', introduction to the course content and educators, useful information for learning together and Glossary

Gene and Protein sequences: Welcome from Anna Protasio your Lead Educator, DNA sequence representation, from DNA to protein

Primary databases: Gene and protein repositories and how they can be used

End of Week 1: Summary of week 1 learning objectives


Week 2

From Sequence to Function


Homology searches: Using public databases to find similar sequences

Biological databases: Introduction to secondary databases with some examples

From sequence to function: From sequence to function, course assessment

Concluding discussion, reflection with next steps, and acknowledgments: End of course discussion and reflection



Who is this accredited by?
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Royal College of Pathologists: 
RCPath has approved this course for 10 CPD credits. This applies to medical staff and clinical scientists in career grade posts who are enrolled with one of the Royal Colleges for CPD purposes.


What will you achieve?

By the end of the course, you‘ll be able to...

  • Assess DNA representations and protein sequences
  • Perform searches in primary databases (repositories) and retrieve gene/protein data
  • Interpret different repository submission formats
  • Investigate biological databases for research
  • Identify the putative function of proteins based on their conserved domains

Who is the course for?

The course will be of interest to undergraduates, post-graduates, researchers, bioinformaticians, biomedical researchers, microbiologists, healthcare professionals and all those who are interested in learning about the underlying mechanisms of bacterial disease, DNA sequences and protein data, or how to use online analytical tools to probe genomes.

The topics covered in this course are applicable to the genomes of all organisms. It is not essential to have previous knowledge or experience in bioinformatics. Scientific terminology is explained. The opportunity to use online computational tools in the context of bacterial genomes will also be of interest to teachers and their 16-18-year-old science and computing students.



Who will you learn with?
  • Dr. Anna Protasio: I am a researcher in parasitology and computational biology at the University of Cambridge. I am passionate about bioinformatics and how we can use these tools to answer questions in biology. 
  • Martin Aslett: I am the IT Manager for the Wellcome Genome Campus Advanced Courses and Scientific Conferences team. My interests lie in bioinformatics and its application to microbial genomics.
  • Dr. Christine Boinett: I am a researcher in bacterial genetics and my interest is in understanding the development of resistance in bacterial pathogens using next generation sequencing techniques. 
  • Professor Nicholas Thomson: I am a Group Leader at the Wellcome Sanger Institute. I provide scientific oversight for this course. I am interested in bacterial evolution and the spread of infectious disease. 
  • Matthew Dorman: I am a graduate student at the Wellcome Sanger Institute, where I research the virulence and the molecular genetics of bacterial pathogens.

Who developed the course?


Wellcome Genome Campus Advanced Courses and Scientific Conferences: 
Wellcome Genome Campus Advanced Courses and Scientific Conferences provides open postgraduate courses and conferences focused on biomedicine.


What's included?

Wellcome Genome Campus Advanced Courses and Scientific Conferences are offering everyone who joins this course a free digital upgrade, so that you can experience the full benefits of studying online for free. This means that you get:

  • Unlimited access to this course
  • Includes any articles, videos, peer reviews and quizzes
  • Tests to validate your learning
  • A PDF Certificate of Achievement to prove your success when you’re eligible

To register and join the course, visit: https://www.futurelearn.com/courses/bacterial-genomes-bioinformatics

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